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OverviewAntibodies are proteins; therefore, methods of purification from biological samples (serum, ascites fluid or culture super-natant) are really specialized forms of general protein purification methods (see the Protein Purification section of the Pierce TechnicalHandbook and Catalog). Antibody purification can be rather crude (as in precipitation of a fraction containing immunoglobulins and other proteins), particular to immunoglobulins as a group or highly specific to only those antibodies in a sample that bind to a given antigen.
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