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Main » 2009 » September » 17 » Efficacy of a Propionibacterium acnes lmmunostimulant for Treatment of Chronic Staphylococcus aureus Mastitis'
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Efficacy of a Propionibacterium acnes lmmunostimulant for Treatment of Chronic Staphylococcus aureus Mastitis'
Efficacy of a Propionibacterium acnes lmmunostimulant for Treatment of
Chronic Staphylococcus aureus Mastitis'

R. P. DINSMORE,2 M. B. CAlTELL, R. D. STEVENS, C. S. GABEL, and M. D. SALMAN
Department of Clinical Sciences

J. K. COLLINS
Diagnostic Laboratory College of Veterinary Medicine and Biomedical Sciences
Colorado State University Fort Collins 80523


ABSTRACT

This study determined the efficacy of treatment of chronic Sraphylococcus aureus IMI of lactating dairy cows with a biological response modifier consisting of a killed preparation of Propionibacrerium acnes. Fifty-one lactating dairy cows with chronic S. aureus MI on two commercial dairies were enrolled in a controlled, randomized field trial. Twenty-four cows received 1 ml of the immunostimulant twice weekly for 4 wk, and the remainder of the cows served as untrested controls. Quarter milk samples were collected for SCC from all cows at 3 and 6 wk after initiation of treatment and for culture at 6 wk after initiation of treatment. If samples were negative for S. aureus at 6 wk, cows were sampled again for culture 1 wk later for 2 succes- sive d before being considered cured. For the cows treated with immunostimulant, 16.7% (36.7% of infected quarters) were cured of S. uureus IMI; for the untreated SOUP, 11.1% Of COWS (32.2% of quaters) were cured. The difference was not statistically significant. Immunostimulant treatment had no effect on quarter SCC in infected quarters overall, but, in those quarters that were cured of S. aureus infection, quarter SCC of treated cows tended to be lower than SCC of control (Key words: mastitis, Sraphylococcus cows. aureus, immunostimulant) Abbreviation key: PA1 = Propionibacterium acnes immunostimulant.

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Category: JOURNAL | Views: 456 | Added by: anis | Tags: Immunostimulant, Sraphylococcus cows. aureus, acnes, Propionibacterium, mastitis | Rating: 0.0/0
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