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Therapy of Experimentally Induced Coliform Mastitis with a Propionibacterium acnes Product'
Therapy of Experimentally Induced Coliform Mastitis with a Propionibacterium acnes Product'
J. S. HOGAN, K. L. SMITH, D. A. TODHUNTER, and P. S. SCHOENBERGER
Department of Dairy Science The Ohio State University Ohio Agricultural Research and Development Center Wooster 44691 1994 J Dairy Sci 77:46247
ABSTRACT
The efficacy of a Propionibacterium acnes product for treatment of coliform mastitis was evaluated following in- tramammary infusion of Escherichia coli. Ten cows were injected in- travenously with a product containing heat-killed P. acnes at 3 h, 3 d, and 7 d after bacterial challenge. Five cows served as untreated negative controls. Bacterial counts in milk, rectal temperatures, and milk SCC did not differ between treated cows and control cows. Intravenous infusion of P. acnes had no effect on milk production or DMI of treated cows compared with untreated controls. Therapy of experimentally in- duced coliform mastitis with a P. acnes product had no effect on seventy or duration of clinical signs.
