|
|
Main » Entries archive
Preparation, Characterization, and Preliminary Application of Fibrinogen-Coated Olive Oil Droplets for the Targeted Delivery of Docetaxel to Solid Malignancies¹
Abhijeet S. Jakate, Charity M. Einhaus, Ashley P. DeAnglis,
Gregory S. Retzinger, and Pankaj B. Desai²
College of Pharmacy [A. S. J., P. B. D.] and Department of Pathology and Laboratory Medicine [C. M. E., A. P. D., G. S. R.], University of Cincinnati, Cincinnati, Ohio 45267
[CANCER RESEARCH 63, 7314–7320, November 1, 2003]
ABSTRACT
Micronized droplets of olive oil loaded with docetaxel (1.0 mg ml)¯¹ and coated with fibrinogen were prepared and then characterized for physicochemical and cytotoxic properties in vitro and anticancer activity in vivo. The droplets
...
Read more »
Category: JOURNAL |
Views: 1325 |
Added by: anis |
Date: 2009-09-17
|
|
Loxoribine Induces Chronic Lymphocytic Leukemia B Cells to Traverse
the Cell Cycle
By Michael G. Goodman, Susan B. Wormsley, John C. Spinosa, and Lawrence D. Piro
© 1994 by The American Society of Hematology.
Wood, Vol 84, No 10 (November 15). 1994: pp 3457-3464
Abstract
Leukemic B cells from a majority of patients with chronic lymphocytic leukemia (CLL) enter the cell cycle upon stimu- lation in vitro with loxoribine, a potent 7,8-disubstituted guanine ribonucleoside immunostimulant. In the absence of added costimulants, a proportion of these cells become acti- vated and undergo DNA synthesis and mitosis accomp
...
Read more »
Category: JOURNAL |
Views: 802 |
Added by: anis |
Date: 2009-09-17
|
|
The Dirt on Herbs: Complementary and Alternative Medicine
Rolee Pathak, Pharm.D., BCPS
Clinical Assistant Professor/Clinical Coordinator Ernest Mario School of Pharmacy/Englewood Hospital and Medical Center
Views: 899 |
Added by: anis |
Date: 2009-09-17
|
|
Liposomes: from biophysics to the design of peptide vaccines
F. Frézard
Departamento de Fisiologia e Biofísica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil
Liposomes as immunoadjuvants Brazilian Journal of Medical and Biological Research (1999) 32: 181-189 ISSN 0100-879X
Abstract
Departamento de Fisiologia e Biofísica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil Liposomes (lipid-based vesicles) have been widely studied as drug delivery systems due to their relative safety, their structural versatility concerning size, composition and bilayer fluidity, and their ability to incorporate almost any molecule regardless of its structure. Liposomes are successful in inducing potent in vivo immunity to i
...
Read more »
Category: JOURNAL |
Views: 903 |
Added by: anis |
Date: 2009-09-17
|
|
Adsorption of Fibrinogen to Droplets of Liquid Hydrophobic Phases: Functionality of the Bound Protein and Biological Implications Gregory S. Retzinger, Ashley P. DeAnglis and Samantha J. Patuto Arterioscler. Thromb. Vasc. Biol. 1998;18;1948-1957 Arteriosclerosis, Thrombosis, and Vascular Biology is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX 72514 Copyright © 1998 American Heart Association. All rights reserved. Print ISSN: 1079-5642. Online ISSN: 1524-4636 Abstract
Fibrinogen adsorbs spontaneously from aqueous media containing that protein to droplets of liquid hydrophobic phases dispersed in those same media. Examples of such phases include mineral oils, straight-chain hydrocarbons, and various plant- and animal-derived oils. Lecithin preexisting on the surface of oil droplets reduces significantly the amount o
...
Read more »
Category: JOURNAL |
Views: 869 |
Added by: anis |
Date: 2009-09-17
|
|
Efficacy of a Propionibacterium acnes lmmunostimulant for Treatment of
Chronic Staphylococcus aureus Mastitis'
R. P. DINSMORE,2 M. B. CAlTELL, R. D. STEVENS, C. S. GABEL, and M. D. SALMAN
Department of Clinical Sciences
J. K. COLLINS
Diagnostic Laboratory College of Veterinary Medicine and Biomedical Sciences
Colorado State University Fort Collins 80523
ABSTRACT
This study determined the efficacy of treatment of chronic Sraphylococcus aureus IMI of lactating dairy cows with a biological response modifier consisting of a killed preparation of Propionibacrerium acnes. Fifty-one lactating dairy cows with chronic S. aureus MI on two commercial dairies were enrolled in a controlled, randomized field trial. Twenty-four cows received 1 ml of the immunostimulant twice weekly for 4 wk, and the remainde
...
Read more »
Category: JOURNAL |
Views: 869 |
Added by: anis |
Date: 2009-09-17
|
|
Effects of fish oil on cytokines and immune functions of mice with murine AIDS
Side Xi,* Donald Cohen,† and Linda H. Chen1,*,§
Nutritional Sciences Program,* Departments of Microbiology and Immunology,† and Nutrition and Food Science,§ University of Kentucky, Lexington, KY 40506-0054
Journal of Lipid Research, Volume 39, 1998
Abstract
The effects of fish oil, which is rich in n–3 fatty acids, on cytokine levels in a murine model of acquired immune deficiency syndrome (AIDS) were studied. Thirty-two C57BL/6 female mice were divided into two dietary groups and fed either a corn oil diet or a fish oil diet. After 4 weeks, each diet group was further divided into two subgroups, and mice in one subgroup were injected i.p. with LP-BM5 murine retrovirus (MAIDS) stock. After 4 weeks, all mice were kill
...
Read more »
Category: JOURNAL |
Views: 839 |
Added by: anis |
Date: 2009-09-17
|
|
Vaccination with Poly-L-Arginine As Immunostimulant for Peptide Vaccines: Induction of Potent and Long-Lasting T-Cell Responses against Cancer AntigensFrank Mattner,1 Julia-Kristina Fleitmann,1 Karen Lingnau, Walter Schmidt, Alena Egyed, Jo¨ rg Fritz, Wolfgang Zauner, Barbara Wittmann, Irmina Gorny, Manfred Berger, Helen Kirlappos, Aleksandr Otava, Max L. Birnstiel, and Michael Buschle2
Intercell Biomedizinische Forschungs und Entwicklungs AG, Rennweg 95B, 1030 Vienna, Austria
[CANCER RESEARCH 62, 1477–1480, March 1, 2002]ABSTRACT
Vaccines that induce high numbers of sustained T cell responses are urgently needed for the treatment of numerous diseases including cancer. Antigen-presenting cells (APCs), the most important of which are dendritic cells, orchestrate antigen-dependent T cell
...
Read more »
Category: JOURNAL |
Views: 857 |
Added by: anis |
Date: 2009-09-17
|
|
Biological activities and medicinal properties of neem (Azadirachta indica)
Kausik Biswas, Ishita Chattopadhyay, Ranajit K. Banerjee* and Uday Bandyopadhyay
Department of Physiology, Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata 700 032, IndiaCURRENT SCIENCE, VOL. 82, NO. 11, 10 JUNE 2002
Abstract
Neem (Azadirachta indica A. Juss) is perhaps the mostuseful traditional medicinal plant in India. Each partof the neem tree has some medicinal property and isthus commercially exploitable. During the last fivedecades, apart from the chemistry of the neem compounds, considerable progress has been achievedregarding the biological activity and medicinal applications of neem. It is now considered as a valuablesource of unique natural products for d
...
Read more »
Category: JOURNAL |
Views: 106119 |
Added by: anis |
Date: 2009-09-17
|
|
Trehalose 6,6 -Dimycolate and Lipid in the Pathogenesis of Caseating Granulomas of Tuberculosis in Mice
Robert L. Hunter, Margaret Olsen, Chinnaswamy Jagannath, and Jeffrey K. Actor
From the Department of Pathology and Laboratory Medicine, University of Texas–Houston Medical School, Houston, Texas
American Journal of Pathology, Vol. 168, No. 4, April 2006 Copyright © American Society for Investigative Pathology DOI: 10.2353/ajpath.2006.050848
Abstract
Trehalose 6,6 -dimycolate (TDM) is the most abundant, most granulomagenic, and most toxic lipid extractable from the surface of virulent Mycobacterium tuberculosis (MTB). We further examined its toxicity, which requires activation by oily surfaces. Injections of MTB and/or TDM i
...
Read more »
Category: JOURNAL |
Views: 8071 |
Added by: anis |
Date: 2009-09-16
|
|
|
| Calendar |
|---|
| « April 2024 » | | Su | Mo | Tu | We | Th | Fr | Sa | | | 1 | 2 | 3 | 4 | 5 | 6 | | 7 | 8 | 9 | 10 | 11 | 12 | 13 | | 14 | 15 | 16 | 17 | 18 | 19 | 20 | | 21 | 22 | 23 | 24 | 25 | 26 | 27 | | 28 | 29 | 30 |
|
| Statistics |
|---|
Total online: 1 Guests: 1 Users: 0 |
|
